Systems Biology

The Systems Biology Lab studies the molecular networks inside cells that give rise to cell behavior and fitness, in isolation and in interaction with other cells and their environment. We focus on the principles and general understanding of how those networks adapt in response to environmental and genetic changes. We combine mathematical modelling, theory, and experiments. We apply the fundamental insights and methods in a biotechnological and biomedical setting.

Systems Biology has four main research themes

• Cell Physiology and Applications
  o   Prof. Frank Bruggeman
  o   Prof. Bas Teusink
  o   Dr. Herwig Bachmann
  o   Dr. Jurgen Haanstra
  o   Dr. Johan van Heerden

• Single-cell metabolism and gene expression regulation
  o   Prof. Frank Bruggeman
  o   Prof. Bas Teusink
  o   Dr. Johan van Heerden
  o   Dr. Evelina Tutucci

• Modeling and Microbial communities
  o   Prof. Frank Bruggeman
  o   Prof. Remco Kort
  o   Prof. Bas Teusink
  o   Dr. Matti Gralka
  o   Dr. Douwe Molenaar

• Host microbe interactions
  o   Prof. Remco Kort
  o   Dr. Rosanne Hertzberger
  o   Dr. Douwe Molenaar